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Bioidentical progesterone has been found not to increase the risk of breast cancer when used in combined hormone therapy with estrogens, while synthetic progestins did increase the risk (Fournier et al. 2005).

After the WHI trial was stopped it was widely reported that the patients receiving combined treatment with estrogen and progestin had a higher incidence of breast cancer than the group receiving estrogen alone, however, bioidentical progesterone was not used in this study.

Endogenous progesterone levels were found not to increase breast cancer risk in the first study to investigate this in postmenopausal women;

this was true even for progesterone receptor positive tumors, which were the most strongly affected by all circulating steroid hormones measured except for progesterone (Missmer et al. 2004). On the other hand, higher levels of endogenous estrogens and androgens were significantly correlated with increasing breast cancer incidence. Kaaks et al. (2005) also found a significant reduction in breast cancer risk in women with high progesterone levels. There is evidence that women with progesterone deficiency have a markedly increased incidence of breast and other cancers (Cowan et al. 1981), and also that the application of progesterone cream to the breasts decreases proliferative activity in breast tissue while estradiol cream increases such activity (Chang et al. 1995). In a study of women undergoing breast tumor excision, those who had higher levels of circulating progesterone at the time of excision had a significantly improved prognosis, the authors concluding that the tumor tissue was not in an actively proliferating state at the time of excision because of progesterone’s antiproliferative effects (Mohr et al. 1996). The role of hormone balance in the development and prevention of breast cancer is still a subject of much controversy. More research is needed in this area. An interesting discussion that is on the edge of new thinking about the role of natural and synthetic hormones in the biochemistry of breast cancer can be found in the book What your doctor may not tell you about breast cancer – how hormone balance can help save your life” by JR Lee, D Zava and V Hopkins, Warner Books, New York 2005. .

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Extracts from the book What your doctor may not tell you about Breast Cancer:

Radiation treatment:

"...Radiation is the most common treatment for brest cancer following surgery, and yet a recent article in the prestigious British medical journal The Lancet showed that this treatment is not working. In fact, while using local radiation to treat breast cancer reduces deaths from this desease by 13.2 percent, it increases death from other causes, mostly heart disease, by 21.2 percent. The obvious conclusion of this study: "The treatment was a success but the patient died"..."

Bold truth about hysterectomy and effectivness of synthetic hormonal drugs

"...The probable cause of the rise in breast cancer deaths was the prescription of unopposed estrogen (not balanced with progesterone) to menopausal women, a common practice from the early 1950s to mid-1970s. While the medical community acknowledged that this practice caused endometrial (uterine) cancer, it never admitted that it is also caused breast cancer. From mid-1970s, doctors were instructed tto prescribe synthetic progestins along with the estrogen to prevent the endometrial cancer. This is also when the incidence of hysterectomy skyrocketed: Women felt so terrible on progestins that they refused to take them, so doctors offered them a hysterectomy so they no longer have to take the progestins, and could take estrogens only. To add insult to injury (literally), it was common practice (and still is in some places) to remove a woman's ovaries along with her uterus as a preventive for ovarian cancer! This misguided practice leads to many other health problems, including osteoporosis, heart disease, fatigue, and a diminished quality of life due to a low libido, hot flashes, and other symptomes of "instant menopause"..."


"...We hope that those promoting tamoxifen remember to mention how many women taking it suffer from blod clots, deterioration of vision, and diminished quality of life (hot flashe, night sweats). Also how many women have been forced to have a hysterectomy due to agressive form of tamoxifen caused uterine cancer. When these women die of uterine cancer instead of breast cancer, it improves the breast cancer statistic. This makes tamoxifen look good, but it's a moot issue to the women in question...."

The truth about mammography

"...For a breast cancer cell to become large enough to be detected by palpation, the cancer has usually been growing for about ten years. If found one year earlier by mammography the cancer has been growing for about nine years (mammography doesn't detect it earlier...), which is plenty of time to spawn metastases if the cancer is prone to do that. the one year difference between palpation and mammography detection is ultimately of little importance...


"...Some chemotherapy does prolonge life for a few months, but generally at the high price of devastating side effects, and if a woman does happen to get lucky and survive that bout of cancer, her body is permanently damaged; recurrence rates are high. The use of chemotherapy is purely a gamble, and we don't think it's worth taking..."

 Success story of breast cancer defeated naturally

"...In contrast Dr. Zava recently had contact with a woman who was given three to six months to live in 1993 because she had a very large, node positive breast cancer tumor. She opted against conventional chemoradiation therapy and began juicing and natural progesterone therapy as an alternative. She called Dr. zava (in 2001) to update him on her progress and to get a saliva test! Granted, this is just one story, but we hear them on a regular basis..."

The bottom line

The bottom line is that a woman with breast cancer is left with few viable options from the medical community. She can't completely trust breast cancer research or recommendations about medical treatments, and she lives in a culture that's averting it's gaze from the real causes of the disease. Thus, it takes enormous courage and fortitude to stand up and take charge of your health, to question your physician and ask for clear answers, and to carefully examine alternatives. We hope that through this book we can inspire you to do just that..."

Natural Progesterone termed by Dr John Lee, M.D. - The Guardian Angel of breast cancer.